Ligand: 47I

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% 7OZYAAA
DFGin BLAplus 2 50.0% 7OZBAAA

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR FGFR1 FGFR1_HUMAN 7OZBAAA 1.71 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 47I Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 7OZBBBB 1.71 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 47I Type1 460 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR2 FGFR2_HUMAN 7OZYAAA 2.28 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 47I Type1 467 - 762 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 7OZYBBB 2.28 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 47I Type1 467 - 762 0 None None Fibroblast growth factor receptor 2

Ligand: 47I

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% 7OZYAAA
DFGin BLAplus 2 50.0% 7OZBAAA

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR FGFR1 FGFR1_HUMAN 7OZBAAA 1.71 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 47I Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 7OZBBBB 1.71 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 47I Type1 460 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 7OZYAAA 2.28 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 47I Type1 467 - 762 0 None None Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 7OZYBBB 2.28 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 47I Type1 467 - 762 0 None None Fibroblast growth factor receptor 2 Homo sapiens

Ligand: 47I

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism