Ligand: 477

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 2 66.7% 3V8TB
DFGin BLAminus 1 33.3% 3VF9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR ITK ITK_HUMAN 3V8TA 2.0 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 477 Type1 357 - 618 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V8TB 2.0 Inactive DFGin‑BLAplus out-none none-none TYR APEdihe_nnnai APEdist_aaan 477 Type1 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK
TYR SYK KSYK_HUMAN 3VF9A 2.3 None DFGin‑BLAminus in-none in-in TYR APEdihe_iiiai APEdist_aaai 477 Type1 364 - 635 0 None None Tyrosine-protein kinase SYK

Ligand: 477

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 2 66.7% 3V8TB
DFGin BLAminus 1 33.3% 3VF9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR ITK ITK_HUMAN 3V8TA 2.0 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 477 Type1 357 - 618 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 3V8TB 2.0 Inactive DFGin‑BLAplus out-none none-none TYR APEdihe_nnnai APEdist_aaan 477 Type1 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR SYK KSYK_HUMAN 3VF9A 2.3 None DFGin‑BLAminus in-none in-in TYR APEdihe_iiiai APEdist_aaai 477 Type1 364 - 635 0 None None Tyrosine-protein kinase SYK Homo sapiens

Ligand: 477

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism