Ligand: 353

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 100.0% 6SDDA

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR MET MET_HUMAN 6SDDA P08581 1062 1344 1390.0 353:1401 Type2 Inactive DFGout 15.67 9.526 BBAminus -149.49, -170.93 -153.94, 114.14 -65.06, -13.55 275.17, 88.26 76.54, -107.92 out-out out 12.411 Saltbr-out 7.347 HRD-in -67.87, -54.54 79.9, -17.29 out-out-in SNCooi out-in ActLoopNT-out 17.253 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -78.26, 119.13 APE9-dihe-in -121.4, 98.95 APE8-dihe-in -84.87, 81.64 APE8-rot-na 25.83 APE67-dihe-in -76.62, 2.13 -39.71, -53.85 APE12-dist-na 11.436 APE11-dist-na 11.546 APE10-dist-na 6.815 APE9-dist-in 6.618 D1228V None None XRAY 1.93 0.211 0.23 A 309 271 12 0 0 0 [[1078, 1339]] 1.0 6sdd TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3F82A P08581 1055 1360 1390.0 353:2001 Type2 Inactive DFGout 15.478 9.639 BBAminus -148.75, -169.98 -153.95, 103.18 -56.5, -43.04 270.25, 97.71 47.11, 999.0 out-out out 10.115 Saltbr-out 5.31 HRD-in -72.25, -53.17 82.39, -19.33 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 37.94 APE9-dihe-in -74.59, 146.36 APE8-dihe-in -82.33, 66.47 APE8-rot-na 33.58 APE67-dihe-in -70.27, -11.92 -52.54, -32.15 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.373 Y1194F,Y1234F,Y1235D None None XRAY 2.5 0.183 0.253 A 314 278 28 0 0 19 [[1078, 1339]] 1.0 3f82 TYR_MET_HUMAN TYR 8.4e-90 306.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor

Ligand: 353

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 100.0% 6SDDA

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR MET MET_HUMAN 6SDDA P08581 1062 1344 1390.0 353:1401 Type2 Inactive DFGout 15.67 9.526 BBAminus -149.49, -170.93 -153.94, 114.14 -65.06, -13.55 275.17, 88.26 76.54, -107.92 out-out out 12.411 Saltbr-out 7.347 HRD-in -67.87, -54.54 79.9, -17.29 out-out-in SNCooi out-in ActLoopNT-out 17.253 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -78.26, 119.13 APE9-dihe-in -121.4, 98.95 APE8-dihe-in -84.87, 81.64 APE8-rot-na 25.83 APE67-dihe-in -76.62, 2.13 -39.71, -53.85 APE12-dist-na 11.436 APE11-dist-na 11.546 APE10-dist-na 6.815 APE9-dist-in 6.618 D1228V None None XRAY 1.93 0.211 0.23 A 309 271 12 0 0 0 [[1078, 1339]] 1.0 6sdd Homo sapiens TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3F82A P08581 1055 1360 1390.0 353:2001 Type2 Inactive DFGout 15.478 9.639 BBAminus -148.75, -169.98 -153.95, 103.18 -56.5, -43.04 270.25, 97.71 47.11, 999.0 out-out out 10.115 Saltbr-out 5.31 HRD-in -72.25, -53.17 82.39, -19.33 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 37.94 APE9-dihe-in -74.59, 146.36 APE8-dihe-in -82.33, 66.47 APE8-rot-na 33.58 APE67-dihe-in -70.27, -11.92 -52.54, -32.15 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.373 Y1194F,Y1234F,Y1235D None None XRAY 2.5 0.183 0.253 A 314 278 28 0 0 19 [[1078, 1339]] 1.0 3f82 Homo sapiens TYR_MET_HUMAN TYR 8.4e-90 306.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor

Ligand: 353

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name