Ligand: 25A

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein

Ligand: 25A

Total number of chains: 6
Active chains: 6
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 100.0% 6M11b

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
OTHER RNASEL A5H025_PIG 6M11A 2.46 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, B49 Allosteric, Type1 22 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 6M11B 2.46 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, B49 Allosteric, Type1 23 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 7DSYA 2.651 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, HFX Allosteric, Type1 22 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 7DSYB 2.651 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, HFX Allosteric, Type1 23 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 7DTSA 2.63 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, 27K Allosteric, Type1 22 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 7DTSB 2.63 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, 27K Allosteric, Type1 23 - 727 0 None None Ribonuclease L Sus scrofa

Ligand: 25A

Total number of chains: 6
Active chains: 6
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 100.0% 6M11b

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
OTHER RNASEL A5H025_PIG 6M11A 2.46 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, B49 Allosteric, Type1 22 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 6M11B 2.46 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, B49 Allosteric, Type1 23 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 7DSYA 2.651 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, HFX Allosteric, Type1 22 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 7DSYB 2.651 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, HFX Allosteric, Type1 23 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 7DTSA 2.63 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, 27K Allosteric, Type1 22 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 7DTSB 2.63 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, 27K Allosteric, Type1 23 - 727 0 None None Ribonuclease L Sus scrofa