AGC_RPS6KA5-1 (Ribosomal protein S6 kinase alpha-5)

Total number of chains: 3
Active chains: 2
Uniprot: KS6A5_HUMAN
Kinase Domain Residues: 49 - 318
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% AF-O75582-K1A
DFGinter None 1 33.3% 1VZOA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-O75582-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 41 - 326 0 None None Ribosomal protein S6 kinase alpha-5
AF-O75582-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 41 - 326 0 None None Ribosomal protein S6 kinase alpha-5
1VZOA 1.8 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iooo No_ligand No_ligand 24 - 345 0 None S212D Ribosomal protein S6 kinase alpha-5

AGC_RPS6KA5-1 (Ribosomal protein S6 kinase alpha-5)

Total number of chains: 3
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% AF-O75582-K1A
DFGinter None 1 33.3% 1VZOA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
KS6A5_HUMAN AF-O75582-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 41 - 326 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
KS6A5_HUMAN AF-O75582-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 41 - 326 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
KS6A5_HUMAN 1VZOA 1.8 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iooo No_ligand No_ligand 24 - 345 0 None S212D Ribosomal protein S6 kinase alpha-5 Homo sapiens

AGC_RPS6KA5-1 (Ribosomal protein S6 kinase alpha-5)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism