TYR_ROR2 (Tyrosine-protein kinase transmembrane receptor ROR2)

Total number of chains: 4
Active chains: 0
Uniprot: ROR2_HUMAN
Kinase Domain Residues: 473 - 748
Spatial label Dihedral label Number of Chains Percent Representative
DFGinter None 3 75.0% 4GT4A
DFGout None 1 25.0% 3ZZWB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
ROR2 3ZZWA Q01974 466 750 943.0 No_ligand No_ligand Pseudo DFGinter 10.345 8.0704 None -96.3, 113.42 -93.32, 36.02 -147.08, 160.59 50.4, 103.61 174.45, -162.31 in-out in 8.4693 Saltbr-out 4.5964 HRD-in -47.14, -51.88 77.11, -23.02 out-out-in SNCooi out-in ActLoopNT-out 17.4441 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -102.81, 114.23 APE9-dihe-in -109.27, 120.13 APE8-dihe-in -82.4, 68.78 APE8-rot-na 28.79 APE67-dihe-in -64.86, -16.77 -44.26, -50.32 APE12-dist-na 13.6266 APE11-dist-na 12.242 APE10-dist-na 7.6275 APE9-dist-in 7.6653 None None None XRAY 2.9 0.19 0.247 A 289.0 269.0 16 30 30 0 [[473, 748]] 1.0 3zzw TYR_ROR2_HUMAN TYR 5.3e-91 310.4 2.0 260.0 259.0 632 633 634 636 638 507 524 528 612 614 613 615.0 674 662 657 656 655 654 653 652 651 554 Tyrosine-protein kinase transmembrane receptor ROR2
ROR2 4GT4A Q01974 464 751 943.0 No_ligand No_ligand Pseudo DFGinter 9.6142 6.4829 None -93.67, 118.8 -119.64, 62.63 -106.27, -3.3 278.25, 67.29 61.48, 39.98 in-out in 8.5333 Saltbr-out 3.8714 HRD-out -75.16, 142.52 -112.65, 2.81 out-out-in SNCooi out-in ActLoopNT-out 16.3143 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -79.46, 127.32 APE9-dihe-in -119.05, 136.77 APE8-dihe-in -80.2, 67.59 APE8-rot-na 30.63 APE67-dihe-in -67.7, -19.84 -54.55, -34.96 APE12-dist-na 15.8936 APE11-dist-na 12.7178 APE10-dist-na 10.2392 APE9-dist-in 6.7475 None None None XRAY 2.406 0.179 0.205 A 308.0 274.0 14 30 30 0 [[473, 748]] 1.0 4gt4 TYR_ROR2_HUMAN TYR 6.7e-91 310.1 2.0 260.0 259.0 632 633 634 636 638 507 524 528 612 614 613 615.0 674 662 657 656 655 654 653 652 651 554 Tyrosine-protein kinase transmembrane receptor ROR2
ROR2 4GT4B Q01974 464 752 943.0 No_ligand No_ligand Pseudo DFGinter 10.1926 7.5819 None -91.01, 100.94 -99.91, 70.26 -110.46, -11.91 297.81, 174.51 61.14, 43.64 in-in in 8.8808 Saltbr-in 2.9749 HRD-in -71.57, -49.3 78.13, -12.79 in-out-in SNCioi out-in ActLoopNT-out 16.1413 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -85.88, 120.55 APE9-dihe-in -112.46, 137.59 APE8-dihe-in -79.18, 69.28 APE8-rot-na 29.96 APE67-dihe-in -69.15, -20.22 -53.97, -34.39 APE12-dist-na 15.7112 APE11-dist-na 12.4476 APE10-dist-na 10.0619 APE9-dist-in 6.7549 None None None XRAY 2.406 0.179 0.205 B 308.0 273.0 16 30 30 0 [[473, 748]] 1.0 4gt4 TYR_ROR2_HUMAN TYR 6.7e-91 310.1 2.0 260.0 259.0 632 633 634 636 638 507 524 528 612 614 613 615.0 674 662 657 656 655 654 653 652 651 554 Tyrosine-protein kinase transmembrane receptor ROR2
ROR2 3ZZWB Q01974 466 750 943.0 No_ligand No_ligand Pseudo DFGout 16.98 12.8631 None -137.59, -157.96 -151.06, 33.97 -68.88, -19.62 62.12, 76.59 -42.22, -63.32 in-out in 8.6709 Saltbr-out 5.0134 HRD-in -47.64, -52.27 76.28, -20.82 out-out-in SNCooi out-in ActLoopNT-out 17.9081 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -102.84, 114.99 APE9-dihe-in -110.43, 119.46 APE8-dihe-in -82.84, 69.13 APE8-rot-na 28.38 APE67-dihe-in -65.02, -16.31 -43.72, -51.28 APE12-dist-na 13.2164 APE11-dist-na 11.5133 APE10-dist-na 6.0808 APE9-dist-in 7.6033 None None None XRAY 2.9 0.19 0.247 B 289.0 265.0 20 30 30 0 [[473, 748]] 1.0 3zzw TYR_ROR2_HUMAN TYR 5.3e-91 310.4 2.0 260.0 259.0 632 633 634 636 638 507 524 528 612 614 613 615.0 674 662 657 656 655 654 653 652 651 554 Tyrosine-protein kinase transmembrane receptor ROR2

TYR_ROR2 (Tyrosine-protein kinase transmembrane receptor ROR2)

Total number of chains: 4
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
DFGinter None 3 75.0% 4GT4A
DFGout None 1 25.0% 3ZZWB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
ROR2 ROR2_HUMAN 3ZZWA Q01974 466 750 943.0 No_ligand No_ligand Pseudo DFGinter 10.345 8.0704 None -96.3, 113.42 -93.32, 36.02 -147.08, 160.59 50.4, 103.61 174.45, -162.31 in-out in 8.4693 Saltbr-out 4.5964 HRD-in -47.14, -51.88 77.11, -23.02 out-out-in SNCooi out-in ActLoopNT-out 17.4441 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -102.81, 114.23 APE9-dihe-in -109.27, 120.13 APE8-dihe-in -82.4, 68.78 APE8-rot-na 28.79 APE67-dihe-in -64.86, -16.77 -44.26, -50.32 APE12-dist-na 13.6266 APE11-dist-na 12.242 APE10-dist-na 7.6275 APE9-dist-in 7.6653 None None None XRAY 2.9 0.19 0.247 A 289.0 269.0 16 30 30 0 [[473, 748]] 1.0 3zzw Homo sapiens TYR_ROR2_HUMAN TYR 5.3e-91 310.4 2.0 260.0 259.0 632 633 634 636 638 507 524 528 612 614 613 615.0 674 662 657 656 655 654 653 652 651 554 Tyrosine-protein kinase transmembrane receptor ROR2
ROR2 ROR2_HUMAN 4GT4A Q01974 464 751 943.0 No_ligand No_ligand Pseudo DFGinter 9.6142 6.4829 None -93.67, 118.8 -119.64, 62.63 -106.27, -3.3 278.25, 67.29 61.48, 39.98 in-out in 8.5333 Saltbr-out 3.8714 HRD-out -75.16, 142.52 -112.65, 2.81 out-out-in SNCooi out-in ActLoopNT-out 16.3143 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -79.46, 127.32 APE9-dihe-in -119.05, 136.77 APE8-dihe-in -80.2, 67.59 APE8-rot-na 30.63 APE67-dihe-in -67.7, -19.84 -54.55, -34.96 APE12-dist-na 15.8936 APE11-dist-na 12.7178 APE10-dist-na 10.2392 APE9-dist-in 6.7475 None None None XRAY 2.406 0.179 0.205 A 308.0 274.0 14 30 30 0 [[473, 748]] 1.0 4gt4 Homo sapiens TYR_ROR2_HUMAN TYR 6.7e-91 310.1 2.0 260.0 259.0 632 633 634 636 638 507 524 528 612 614 613 615.0 674 662 657 656 655 654 653 652 651 554 Tyrosine-protein kinase transmembrane receptor ROR2
ROR2 ROR2_HUMAN 4GT4B Q01974 464 752 943.0 No_ligand No_ligand Pseudo DFGinter 10.1926 7.5819 None -91.01, 100.94 -99.91, 70.26 -110.46, -11.91 297.81, 174.51 61.14, 43.64 in-in in 8.8808 Saltbr-in 2.9749 HRD-in -71.57, -49.3 78.13, -12.79 in-out-in SNCioi out-in ActLoopNT-out 16.1413 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -85.88, 120.55 APE9-dihe-in -112.46, 137.59 APE8-dihe-in -79.18, 69.28 APE8-rot-na 29.96 APE67-dihe-in -69.15, -20.22 -53.97, -34.39 APE12-dist-na 15.7112 APE11-dist-na 12.4476 APE10-dist-na 10.0619 APE9-dist-in 6.7549 None None None XRAY 2.406 0.179 0.205 B 308.0 273.0 16 30 30 0 [[473, 748]] 1.0 4gt4 Homo sapiens TYR_ROR2_HUMAN TYR 6.7e-91 310.1 2.0 260.0 259.0 632 633 634 636 638 507 524 528 612 614 613 615.0 674 662 657 656 655 654 653 652 651 554 Tyrosine-protein kinase transmembrane receptor ROR2
ROR2 ROR2_HUMAN 3ZZWB Q01974 466 750 943.0 No_ligand No_ligand Pseudo DFGout 16.98 12.8631 None -137.59, -157.96 -151.06, 33.97 -68.88, -19.62 62.12, 76.59 -42.22, -63.32 in-out in 8.6709 Saltbr-out 5.0134 HRD-in -47.64, -52.27 76.28, -20.82 out-out-in SNCooi out-in ActLoopNT-out 17.9081 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -102.84, 114.99 APE9-dihe-in -110.43, 119.46 APE8-dihe-in -82.84, 69.13 APE8-rot-na 28.38 APE67-dihe-in -65.02, -16.31 -43.72, -51.28 APE12-dist-na 13.2164 APE11-dist-na 11.5133 APE10-dist-na 6.0808 APE9-dist-in 7.6033 None None None XRAY 2.9 0.19 0.247 B 289.0 265.0 20 30 30 0 [[473, 748]] 1.0 3zzw Homo sapiens TYR_ROR2_HUMAN TYR 5.3e-91 310.4 2.0 260.0 259.0 632 633 634 636 638 507 524 528 612 614 613 615.0 674 662 657 656 655 654 653 652 651 554 Tyrosine-protein kinase transmembrane receptor ROR2

TYR_ROR2 (Tyrosine-protein kinase transmembrane receptor ROR2)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name