CAMK_MARK3 (MAP/microtubule affinity-regulating kinase 3)

Total number of chains: 16
Active chains: 2
Uniprot: MARK3_HUMAN
Kinase Domain Residues: 56 - 307
Spatial label Dihedral label Number of Chains Percent Representative
None None 9 56.2% 3FE3A
DFGin BLAminus 5 31.2% AF-P27448-K1A
DFGin BLBminus 1 6.2% 7P1LA
DFGin BLBtrans 1 6.2% 8UOJA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P27448-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 48 - 315 0 None None MAP/microtubule affinity-regulating kinase 3
AF-P27448-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 48 - 315 0 None None MAP/microtubule affinity-regulating kinase 3
8UOIA 1.8 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iooi X3Q Type1 51 - 368 0 None I62L,L72R,V116I,G137K,F141Y,A146E,V205K MAP/microtubule affinity-regulating kinase 3
8UOKA 1.85 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooi X5N Type1 51 - 369 0 None I62L,L72R,V116I,G137K,F141Y,A146E,V205K MAP/microtubule affinity-regulating kinase 3
8UOKB 1.85 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooi X5N Type1 51 - 369 0 None I62L,L72R,V116I,G137K,F141Y,A146E,V205K MAP/microtubule affinity-regulating kinase 3
7P1LA 1.95 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn V5E Type1 50 - 365 0 None None MAP/microtubule affinity-regulating kinase 3
8UOJA 1.6 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaioi APEdist_oooi X5I, BEZ Type1, Allosteric 50 - 370 0 None I62L,L72R,V116I,G137K,F141Y,A146E MAP/microtubule affinity-regulating kinase 3
2QNJA 2.7 Inactive None‑None in-out out-out nonTYR APEdihe_aaooi APEdist_iooo No_ligand No_ligand 44 - 366 0 None None MAP/microtubule affinity-regulating kinase 3
2QNJB 2.7 Inactive None‑None out-out out-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 44 - 367 0 None None MAP/microtubule affinity-regulating kinase 3
3FE3A 1.9 Inactive None‑None out-out out-out nonTYR APEdihe_aaoni APEdist_iooo No_ligand No_ligand 50 - 366 0 None T211A,S215A MAP/microtubule affinity-regulating kinase 3
3FE3B 1.9 Inactive None‑None out-out out-out nonTYR APEdihe_aaoni APEdist_iooo No_ligand No_ligand 50 - 366 0 None T211A,S215A MAP/microtubule affinity-regulating kinase 3
8UOHA 2.15 Inactive None‑None out-out out-out nonTYR APEdihe_aaooi APEdist_iooo No_ligand No_ligand 48 - 369 0 None I62L,L72R,V116I,G137K,F141Y,A146E MAP/microtubule affinity-regulating kinase 3
7P1LB 1.95 Inactive None‑None out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn V5E Type1 50 - 365 0 None None MAP/microtubule affinity-regulating kinase 3
8UOHB 2.15 Inactive None‑None in-out out-out nonTYR APEdihe_aaooi APEdist_iooo X4W Type1 48 - 370 0 None I62L,L72R,V116I,G137K,F141Y,A146E MAP/microtubule affinity-regulating kinase 3
8UOLA 1.9 Inactive None‑None out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn X4H Type1 51 - 370 0 None I62L,L72R,V116I,G137K,F141Y,A146E MAP/microtubule affinity-regulating kinase 3
8UOLB 1.9 Inactive None‑None out-out out-out nonTYR APEdihe_aaooi APEdist_nnni X4H Type1 50 - 367 0 None I62L,L72R,V116I,G137K,F141Y,A146E MAP/microtubule affinity-regulating kinase 3

CAMK_MARK3 (MAP/microtubule affinity-regulating kinase 3)

Total number of chains: 16
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
None None 9 56.2% 3FE3A
DFGin BLAminus 5 31.2% AF-P27448-K1A
DFGin BLBminus 1 6.2% 7P1LA
DFGin BLBtrans 1 6.2% 8UOJA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
MARK3_HUMAN AF-P27448-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 48 - 315 0 None None MAP/microtubule affinity-regulating kinase 3 Homo sapiens
MARK3_HUMAN AF-P27448-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 48 - 315 0 None None MAP/microtubule affinity-regulating kinase 3 Homo sapiens
MARK3_HUMAN 8UOIA 1.8 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iooi X3Q Type1 51 - 368 0 None I62L,L72R,V116I,G137K,F141Y,A146E,V205K MAP/microtubule affinity-regulating kinase 3 Homo sapiens
MARK3_HUMAN 8UOKA 1.85 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooi X5N Type1 51 - 369 0 None I62L,L72R,V116I,G137K,F141Y,A146E,V205K MAP/microtubule affinity-regulating kinase 3 Homo sapiens
MARK3_HUMAN 8UOKB 1.85 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooi X5N Type1 51 - 369 0 None I62L,L72R,V116I,G137K,F141Y,A146E,V205K MAP/microtubule affinity-regulating kinase 3 Homo sapiens
MARK3_HUMAN 7P1LA 1.95 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn V5E Type1 50 - 365 0 None None MAP/microtubule affinity-regulating kinase 3 Homo sapiens
MARK3_HUMAN 8UOJA 1.6 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaioi APEdist_oooi X5I, BEZ Type1, Allosteric 50 - 370 0 None I62L,L72R,V116I,G137K,F141Y,A146E MAP/microtubule affinity-regulating kinase 3 Homo sapiens
MARK3_HUMAN 2QNJA 2.7 Inactive None‑None in-out out-out nonTYR APEdihe_aaooi APEdist_iooo No_ligand No_ligand 44 - 366 0 None None MAP/microtubule affinity-regulating kinase 3 Homo sapiens
MARK3_HUMAN 2QNJB 2.7 Inactive None‑None out-out out-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 44 - 367 0 None None MAP/microtubule affinity-regulating kinase 3 Homo sapiens
MARK3_HUMAN 3FE3A 1.9 Inactive None‑None out-out out-out nonTYR APEdihe_aaoni APEdist_iooo No_ligand No_ligand 50 - 366 0 None T211A,S215A MAP/microtubule affinity-regulating kinase 3 Homo sapiens
MARK3_HUMAN 3FE3B 1.9 Inactive None‑None out-out out-out nonTYR APEdihe_aaoni APEdist_iooo No_ligand No_ligand 50 - 366 0 None T211A,S215A MAP/microtubule affinity-regulating kinase 3 Homo sapiens
MARK3_HUMAN 8UOHA 2.15 Inactive None‑None out-out out-out nonTYR APEdihe_aaooi APEdist_iooo No_ligand No_ligand 48 - 369 0 None I62L,L72R,V116I,G137K,F141Y,A146E MAP/microtubule affinity-regulating kinase 3 Homo sapiens
MARK3_HUMAN 7P1LB 1.95 Inactive None‑None out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn V5E Type1 50 - 365 0 None None MAP/microtubule affinity-regulating kinase 3 Homo sapiens
MARK3_HUMAN 8UOHB 2.15 Inactive None‑None in-out out-out nonTYR APEdihe_aaooi APEdist_iooo X4W Type1 48 - 370 0 None I62L,L72R,V116I,G137K,F141Y,A146E MAP/microtubule affinity-regulating kinase 3 Homo sapiens
MARK3_HUMAN 8UOLA 1.9 Inactive None‑None out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn X4H Type1 51 - 370 0 None I62L,L72R,V116I,G137K,F141Y,A146E MAP/microtubule affinity-regulating kinase 3 Homo sapiens
MARK3_HUMAN 8UOLB 1.9 Inactive None‑None out-out out-out nonTYR APEdihe_aaooi APEdist_nnni X4H Type1 50 - 367 0 None I62L,L72R,V116I,G137K,F141Y,A146E MAP/microtubule affinity-regulating kinase 3 Homo sapiens

CAMK_MARK3 (MAP/microtubule affinity-regulating kinase 3)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism