8UOH

MARK3 (MAP/microtubule affinity-regulating kinase 3)
Group: CAMK
Uniprot: MARK3_HUMAN
Organism: Homo sapiens
Domain boundary: 56 - 307
Resolu: 2.15

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive None None out-out out-out No_ligand No_ligand 48 - 369 0
B Inactive None None in-out out-out X4W Type1 48 - 370 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
        52         62         72         82 
GAMGSDEQPH IGNYRLLKTL GKGNFAKVKR ARHILTGREV 
        92        102        112        122 
AIKIIDKTQL NPTSLQKLFR EVRIMKILNH PNIIKLFEVI 
       132        142        152        162 
ETEKTLYLIM EYASKGEVYD YLVEHGRMKE KEARSKFRQI 
       172        182        192        202 
VSAVQYCHQK RIVHRDLKAE NLLLDADMNI KIADFGFSNE 
       212        222        232        242 
FTVGGKLDTF CGSPPYAAPE LFQGKKYDGP EVDVWSLGVI 
       252        262        272        282 
LYTLVSGSLP FDGQNLKELR ERVLRGKYRI PFYMSTDCEN 
       292        302        312        322 
LLKRFLVLNP IKRGTLEQIM KDRWINAGHE EDELKPFVEP 
       332        342        352        362 
ELDISDQKRI DIMVGMGYSQ EEIQESLSKM KYDEITATYL 

LLGRKSSE
Lower-case residues are disordered in structure.
Mutations: I62L,L72R,V116I,G137K,F141Y,A146E
Phosphorylation: None