AGC_GRK4 (G protein-coupled receptor kinase 4)

Total number of chains: 4
Active chains: 4
Uniprot: GRK4_HUMAN
Kinase Domain Residues: 187 - 449
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% AF-P32298-K1A

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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
4YHJA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 25 - 525 0 None C563S,C578S G protein-coupled receptor kinase 4
4YHJB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 25 - 527 0 None C563S,C578S G protein-coupled receptor kinase 4
AF-P32298-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 179 - 457 0 None None G protein-coupled receptor kinase 4
AF-P32298-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 179 - 457 0 None None G protein-coupled receptor kinase 4

AGC_GRK4 (G protein-coupled receptor kinase 4)

Total number of chains: 4
Active chains: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% AF-P32298-K1A

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
GRK4_HUMAN 4YHJA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 25 - 525 0 None C563S,C578S G protein-coupled receptor kinase 4 Homo sapiens
GRK4_HUMAN 4YHJB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 25 - 527 0 None C563S,C578S G protein-coupled receptor kinase 4 Homo sapiens
GRK4_HUMAN AF-P32298-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 179 - 457 0 None None G protein-coupled receptor kinase 4 Homo sapiens
GRK4_HUMAN AF-P32298-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 179 - 457 0 None None G protein-coupled receptor kinase 4 Homo sapiens

AGC_GRK4 (G protein-coupled receptor kinase 4)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism