TYR_EPHA4 (Ephrin type-A receptor 4)

Total number of chains: 2
Active chains: 2
Uniprot: EPHA4_HUMAN
Kinase Domain Residues: 621 - 880
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P54764-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P54764-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 613 - 888 0 None None Ephrin type-A receptor 4
AF-P54764-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 613 - 888 0 None None Ephrin type-A receptor 4

TYR_EPHA4 (Ephrin type-A receptor 4)

Total number of chains: 6
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 50.0% AF-P54764-K1A
DFGin None 3 50.0% 2Y6OA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
EPHA4_HUMAN AF-P54764-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 613 - 888 0 None None Ephrin type-A receptor 4 Homo sapiens
EPHA4_HUMAN AF-P54764-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 613 - 888 0 None None Ephrin type-A receptor 4 Homo sapiens
EPHA4_MOUSE 2Y6MA 1.7 Inactive DFGin‑None in-in none-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 609 - 891 0 None None Ephrin type-A receptor 4 Mus musculus
EPHA4_MOUSE 2Y6OA 1.543 Inactive DFGin‑None in-in none-none TYR APEdihe_nniai APEdist_aaai 1N1 Type1 609 - 891 0 None None Ephrin type-A receptor 4 Mus musculus
EPHA4_MOUSE 2XYUA 2.117 Inactive DFGin‑None in-out none-none TYR APEdihe_nniai APEdist_aaai Q9G Type1.5_Back 612 - 891 0 None None Ephrin type-A receptor 4 Mus musculus
EPHA4_MOUSE 2HELA 2.35 None DFGin‑BLAminus in-in in-none TYR APEdihe_niiai APEdist_aaai No_ligand No_ligand 613 - 888 0 None Y596F,Y602F,Y742A Ephrin type-A receptor 4 Mus musculus

TYR_EPHA4 (Ephrin type-A receptor 4)

Total number of chains: 4
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 3 75.0% 2Y6OA
DFGin BLAminus 1 25.0% 2HELA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
EPHA4_MOUSE 2Y6MA 1.7 Inactive DFGin‑None in-in none-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 609 - 891 0 None None Ephrin type-A receptor 4 Mus musculus
EPHA4_MOUSE 2Y6OA 1.543 Inactive DFGin‑None in-in none-none TYR APEdihe_nniai APEdist_aaai 1N1 Type1 609 - 891 0 None None Ephrin type-A receptor 4 Mus musculus
EPHA4_MOUSE 2XYUA 2.117 Inactive DFGin‑None in-out none-none TYR APEdihe_nniai APEdist_aaai Q9G Type1.5_Back 612 - 891 0 None None Ephrin type-A receptor 4 Mus musculus
EPHA4_MOUSE 2HELA 2.35 None DFGin‑BLAminus in-in in-none TYR APEdihe_niiai APEdist_aaai No_ligand No_ligand 613 - 888 0 None Y596F,Y602F,Y742A Ephrin type-A receptor 4 Mus musculus