TYR_DDR2 (Discoidin domain-containing receptor 2)

Total number of chains: 15
Active chains: 2
Uniprot: DDR2_HUMAN
Kinase Domain Residues: 563 - 851
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 13 86.7% 6FERD
DFGin BLAminus 2 13.3% AF-Q16832-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q16832-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 555 - 855 0 None None Discoidin domain-containing receptor 2
AF-Q16832-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 555 - 855 0 None None Discoidin domain-containing receptor 2
6FERD 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type1 553 - 851 0 None None Discoidin domain-containing receptor 2
6FERI 2.87 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type1 555 - 851 0 None None Discoidin domain-containing receptor 2
6FERA 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
6FERB 2.87 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
6FERC 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
6FERE 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
6FERF 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
6FERG 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
6FERH 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
6FERJ 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
6FERK 2.87 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 555 - 851 0 None None Discoidin domain-containing receptor 2
6FERL 2.87 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 554 - 851 0 None None Discoidin domain-containing receptor 2
7AYMA 2.12 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 4VD Type2 558 - 849 0 None K826E,L847R Discoidin domain-containing receptor 2

TYR_DDR2 (Discoidin domain-containing receptor 2)

Total number of chains: 15
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 13 86.7% 6FERD
DFGin BLAminus 2 13.3% AF-Q16832-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
DDR2_HUMAN AF-Q16832-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 555 - 855 0 None None Discoidin domain-containing receptor 2 Homo sapiens
DDR2_HUMAN AF-Q16832-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 555 - 855 0 None None Discoidin domain-containing receptor 2 Homo sapiens
DDR2_HUMAN 6FERD 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type1 553 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
DDR2_HUMAN 6FERI 2.87 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type1 555 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
DDR2_HUMAN 6FERA 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
DDR2_HUMAN 6FERB 2.87 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
DDR2_HUMAN 6FERC 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
DDR2_HUMAN 6FERE 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
DDR2_HUMAN 6FERF 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
DDR2_HUMAN 6FERG 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
DDR2_HUMAN 6FERH 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
DDR2_HUMAN 6FERJ 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
DDR2_HUMAN 6FERK 2.87 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 555 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
DDR2_HUMAN 6FERL 2.87 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 554 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
DDR2_HUMAN 7AYMA 2.12 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 4VD Type2 558 - 849 0 None K826E,L847R Discoidin domain-containing receptor 2 Homo sapiens

TYR_DDR2 (Discoidin domain-containing receptor 2)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism