8PQE

KIT (Mast/stem cell growth factor receptor Kit)
Group: TYR
Uniprot: KIT_HUMAN
Organism: Homo sapiens
Domain boundary: 589 - 926
Resolu: 2.0

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive None None in-in none-in 9WU Type1 566 - 930 19
B Active DFGin BLAminus in-in in-in 9WU Type1 566 - 930 13
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       557        567        577        587 
gsmpmyevqw kvveesngNN YSYIDPTQLP YDHKWEFPRN 
       597        607        617        627 
RLSFGKTLGA GAFGKVVEAT AQGLIKSDAA MTVAVKMLKP 
       637        647        657        667 
SAHSTEREAL MSELKVLSYL GNHENIVNLL GACTHGGPTL 
       677        687          -        767 
VITEYCCYGD LLNFLRRKRD EFVPYkvape dlykDFLTLE 
       777        787        797        807 
HLLSFSYQVA KGMAFLASKN CIHRDLAARN ILLTHGNITK 
       817        827        837        847 
ICDFGLARDi kndsnyvdkg naRLPVKWMA PESIFNSVYT 
       857        867        877        887 
FESDVWSYGI FLWELFSLGS SPYPGMPVDS KFYKMIKEGF 
       897        907        917        927 
RMSSPEYAPA EMYDIMKTCW DADPDKRPTF KQIVQDIEKQ 

ISEstnh
Lower-case residues are disordered in structure.
Mutations: I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D
Phosphorylation: None