8JOT

CSF1R (Macrophage colony-stimulating factor 1 receptor)
Group: TYR
Uniprot: CSF1R_HUMAN
Organism: Homo sapiens
Domain boundary: 582 - 912
Resolu: 1.69

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout BBAminus in-in out-in UKI Type1 543 - 914 1
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         -        550        560        570 
mkkghhhhhh gqKPKYQVRW KIIESyegns YTFIDPTQLP 
       580        590        600        610 
YNEKWEFPRN NLQFGKTLGA GAFGKVVEAT AFGLGKEDAV 
       620        630        640        650 
LKVAVKMLKS TAHADEKEAL MSELKIMSHL GQHENIVNLL 
       660        670        680        690 
GACTHGGPVL VITEYCTYGD LLNFLRRKAE AMLGPSlspg 
       700        745        755        765 
qdpeggvdyk nihlekldke dGRPLELRDL LHFSSQVAQG 
       775        785        795        805 
MAFLASKNCI HRDVAARNVL LTNGHVAKIG DFGLARDIMN 
       815        825        835        845 
DSNYIVKGnA RLPVKWMAPE SIFDSVYTVQ SDVWSYGILL 
       855        865        875        885 
WEIFSLGLNP YPGILVNSKF YKLVKDGYQM AQPAFAPKNI 
       895        905        915 
YSIMQACWAL EPTHRPTFQQ ITSFLQEQAq edrr
Lower-case residues are disordered in structure.
Mutations: C667T,C830S,C907T
Phosphorylation: None