8J5X

NTRK1 (High affinity nerve growth factor receptor)
Group: TYR
Uniprot: NTRK1_HUMAN
Organism: Homo sapiens
Domain boundary: 510 - 783
Resolu: 2.092

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout BBAminus in-in out-in A4U Type2 500 - 795 0
Representative sequence - Chain A
507 517 527 537
sdACVHHIKR RDIVLKWELG EGAFGKVFLA ECHNLLPEQD
547 557 567 577
KMLVAVKALK EASESARQDF QREAELLTML QHQHIVRFFG
587 597 607 617
VCTEGRPLLM VFEYMRHRDL NRFLRSHGPD AKLLAGGEDV
627 637 647 657
APGPLGLGQL LAVASQVAAG MVYLAGLHFV HRDLATRNCL
667 677 687 697
VGQGLVVKIG DFGMSRDIYS TDYYRVGGRT MLPIRWMPPE
707 717 727 737
SILYRKFTTE SDVWSFGVVL WEIFTYGKQP WYQLSNTEAI
747 757 767 777
DCITQGRELE RPRACPPEVY AIMRGCWQRE PQQRHSIKDV
787
HARLQALAQA PPVYLDVLg
Lower-case residues are disordered in structure.
Mutations: G595R
Phosphorylation: None