8J5W

NTRK1 (High affinity nerve growth factor receptor)
Group: TYR
Uniprot: NTRK1_HUMAN
Organism: Homo sapiens
Domain boundary: 510 - 783
Resolu: 2.28

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout None in-out out-in A4U Type2 485 - 795 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       493        503        513        523 
sGLQGHiien pqyfsDACVH HIKRRDIVLK WELGEGAFGK 
       533        543        553        563 
VFLAECHNLL PEQDKMLVAV KALKEasESA RQDFQREAEL 
       573        583        593        603 
LTMLQHQHIV RFFGVCTEGR PLLMVLEYMR HGDLNRFLRS 
       613        623        633        643 
HGPDakLLAG GEDVAPGPLG LGQLLAVASQ VAAGMVYLAG 
       653        663        673        683 
LHFVHRDLAT RNCLVGQGLV VKIGDFGMSR DIYSTDYYRV 
       693        703        713        723 
GGRTMLPIRW MPPESILYRK FTTESDVWSF GVVLWEIFTY 
       733        743        753        763 
GKQPWYQLSN TEAIDCITQG RELERPRACP PEVYAIMRGC 
       773        783        793 
WQREPQQRHS IKDVHARLQA LAQAPPVYLD VLg
Lower-case residues are disordered in structure.
Mutations: F589L
Phosphorylation: None