| Chain id | Activity_label | Spatial_label | Dihedral_label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|
| X6 | Active | DFGin | BLAminus | out-in | in-in | No_ligand | No_ligand | 3 - 269 | 0 |
| X7 | Inactive | DFGin | BLAminus | out-out | in-in | No_ligand | No_ligand | 3 - 269 | 0 |
| X8 | Inactive | DFGin | BLAminus | out-out | in-in | No_ligand | No_ligand | 3 - 269 | 0 |
Representative sequence - Chain X8
10 20 30 40
msGDKLLSEL GYKLGRTIGE GSYSKVKVAT SKKYKGTVAI
50 60 70 80
KVVDRRRAPP DFVNKFLPRE LSILRGVRHP HIVHVFEFIE
90 100 110 120
VCNGKLYIVM EAAATDLLQA VQRNGRIPGS QARELFSQIA
130 140 150 160
GAVRYLHDHH LVHRDLKCEN VLLSPDERRV KITDFGFGRQ
170 180 190 200
AHGYPDLSTT YCGSAAYASP EVLLGIPYDP KKYDVWSLGV
210 220 230 240
VLYVMVTGCM PFDDSDIAGL PRRQKRGVLY PDGLELSERC
250 260 270
KSLIAELLQF SPSARPSAGQ VARNGWLRAg dsg