8E1X

FGFR2 (Fibroblast growth factor receptor 2)
Group: TYR
Uniprot: FGFR2_HUMAN
Organism: Homo sapiens
Domain boundary: 481 - 759
Resolu: 2.68

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAplus in-in out-out U9P Type1 468 - 762 5
B Inactive DFGin BLAplus in-in out-out U9P Type1 467 - 765 2
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         -          -        468        478 
mgsshhhhhh ssglvprgsh mlagvseyEL PEDPKWEFPR 
       488        498        508        518 
DKLTLGKPLG EGAFGQVVMA EAVGIDKDKP KEAVTVAVKM 
       528        538        548        558 
LKdDATEKDL SDLVSEMEMM KMIGKHKNII NLLGACTQDG 
       568        578        588        598 
PLYVIVEYAS KGNLREYLRA RRPPGMEYSY DINRvpeEQM 
       608        618        628        638 
TFKDLVSCTY QLARGMEYLA SQKCIHRDLA ARNVLVTENN 
       648        658        668        678 
VMKIADFGLA RDINniDYYK KTTNGRLPVK WMAPEALFDR 
       688        698        708        718 
VYTHQSDVWS FGVLMWEIFT LGGSPYPGIP VEELFKLLKE 
       728        738        748        758 
GHRMDKPANC TNELYMMMRD CWHAVPSQRP TFKQLVEDLD 
       768 
RILTLTTnee
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X561,X586