8ANS

MET (Hepatocyte growth factor receptor)
Group: TYR
Uniprot: MET_HUMAN
Organism: Homo sapiens
Domain boundary: 1076 - 1339
Resolu: 2.01

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout BBAminus out-none in-in MDI Type1.5_Front 1052 - 1346 15
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
      1060       1070       1080       1090 
gHIDLSALNP ELVQAVQHVV IGPSSLIVHF NEVIGRGHFG 
      1100       1110       1120       1130 
CVYHGTLLDn dgKKIHCAVK SLNRITDIGE VSQFLTEGII 
      1140       1150       1160       1170 
MKDFSHPNVL SLLGICLRSE GSPLVVLPYM KHGDLRNFIR 
      1180       1190       1200       1210 
NETHNPTVKD LIGFGLQVAK GMKYLASKKF VHRDLAARNC 
      1220       1230       1240       1250 
MLDEKFTVKV ADFGLARVMy dkeyysvhnk tgakLPVKWM 
      1260       1270       1280       1290 
ALESLQTQKF TTKSDVWSFG VLLWELMTRG APPYPDVNTF 
      1300       1310       1320       1330 
DITVYLLQGR RLLQPEYCPD PLYEVMLKCW HPKAEMRPSF 
      1340 
SELVSRISAI FSTFIG
Lower-case residues are disordered in structure.
Mutations: D1228V
Phosphorylation: None