7UY0

FGR (Tyrosine-protein kinase Fgr)
Group: TYR
Uniprot: FGR_HUMAN
Organism: Homo sapiens
Domain boundary: 263 - 514
Resolu: 2.55

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLBplus out-out out-in VSE Type1.5_Back 80 - 527 0
B Inactive DFGin BLBplus out-out out-out VSE Type1.5_Back 80 - 527 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
        81         91        101        111 
mghhhhhhTL FIALYDYEAR TEDDLTFTKG EKFHILNNTE 
       121        131        141        151 
GDWWEARSLS SGKTGCIPSN YVAPVDSIQA EEWYFGKIGR 
       161        171        181        191 
KDAERQLLSP GNPQGAFLIR ESETTKGAYS LSIRDWDQTR 
       201        211        221        231 
GDHVKHYKIR KLDMGGYYIT TRVQFNSVQE LVQHYMEVND 
       241        251        261        271 
GLCNLLIAPC TIMKPQTLGL AKDAWEISRS SITLERRLGT 
       281        291        301        311 
GCFGDVWLGT WNGSTKVAVK TLKPGTMSPK AFLEEAQVMK 
       321        331        341        351 
LLRHDKLVQL YAVVSEEPIY IVTEFMCHGS LLDFLKNPEG 
       361        371        381        391 
QDLRLPQLVD MAAQVAEGMA YMERMNYIHR DLRAANILVG 
       401        411        421        431 
ERLACKIADF GLARLIKDDE YNPCQGSKFP IKWTAPEAAL 
       441        451        461        471 
FGRFTIKSDV WSFGILLTEL ITKGRIPYPG MNKREVLEQV 
       481        491        501        511 
EQGYHMPCPP GCPASLYEAM EQTWRLDPEE RPTFEYLQSF 
       521 
LEDYFTSAEP QYEEIP
Lower-case residues are disordered in structure.
Mutations: Q524E,P525E,G526I,D527P
Phosphorylation: X523