7KIA

FGFR2 (Fibroblast growth factor receptor 2)
Group: TYR
Uniprot: FGFR2_HUMAN
Organism: Homo sapiens
Domain boundary: 481 - 759
Resolu: 2.22

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in WFD Type1 467 - 764 0
B Active DFGin BLAminus in-in in-in WFD Type1 467 - 767 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       470        480        490        500 
agvseyELPE DPKWEFPRDK LTLGKPLGEG CFGQVVMAEA 
       510        520        530        540 
VGIDKDKPKE AVTVAVKMLK DDATEKDLSD LVSEMEMMKM 
       550        560        570        580 
IGKHKNIINL LGACTQDGPL YVIFEYASKG NLREYLRARR 
       590        600        610        620 
PPgmeysydi nrvpeEQMTF KDLVSCTYQL ARGMEYLASQ 
       630        640        650        660 
KCIHRDLAAR NVLVTENNVM KIADFGLARD INNIDYYKKT 
       670        680        690        700 
TNGRLPVKWM APEALFDRVY THQSDVWSFG VLMWEIFTLG 
       710        720        730        740 
GSPYPGIPVE ELFKLLKEGH RMDKPANCTN ELYMMMRDCW 
       750        760 
HAVPSQRPTF KQLVEDLDRI LTLTTNEe
Lower-case residues are disordered in structure.
Mutations: V564F
Phosphorylation: None