6XIH

MAP3K5 (Mitogen-activated protein kinase kinase kinase 5)
Group: STE
Uniprot: M3K5_HUMAN
Organism: Homo sapiens
Domain boundary: 673 - 938
Resolu: 2.65

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in V3S Type1 671 - 940 8
B Active DFGin BLAminus in-in in-in V3S Type1 671 - 939 12
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       675        685        695        705 
mesdlLEYDY EYDENGDRVV LGKGTYGIVY AGRDLSNQVR 
       715        725        735        745 
IAIKEIPERD srysqPLHEE IALHKHLKHK NIVQYLGSFS 
       755        765        775        785 
ENGFIKIFME QVPGGSLSAL LRSKWGPLKD NEQTIGFYTK 
       795        805        815        825 
QILEGLKYLH DNQIVHRDIK GDNVLINTYS GVLKISDFGT 
       835        845        855        865 
SKRlaginpc tetftGTLQY MAPEIIDkgp rgYGKAADIW 
       875        885        895        905 
SLGCTIIEMA TGKPPFYElG EPQAAMFKVG MFKVHPEIPE 
       915        925        935        945 
SMSAEAKAFI LKCFEPDPDK RACANDLLVD EFLKvsskkk 
         - 
ktqpklsash hhhhh
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None