6VPH

AURKA (Aurora kinase A)
Group: CAMK
Uniprot: AURKA_HUMAN
Organism: Homo sapiens
Domain boundary: 133 - 383
Resolu: 2.14

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout None out-out out-out ANP Type1 7 - 389 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
        12        117        127        137 
gaHMSYSYDA PSDFINFSSk qkneeSKKRQ WALEDFEIGR 
       147        157        167        177 
PLGKGKFGNV YLAREKQSKF ILALKVLFKA QLEKAGVEHQ 
       187        197        207        217 
LRREVEIQSH LRHPNILRLY GYFHDATRVY LILEYAPLGT 
       227        237        247        257 
VYRELQKLSK FDEQRTATYI TELANALSYC HSKRVIHRDI 
       267        277        287        297 
KPENLLLGSA GELKIADFGW SVHAPSSRRT TLCGTLDYLP 
       307        317        327        337 
PEMIEGRMHD EKVDLWSLGV LCYEFLVGKP PFEANTYQET 
       347        357        367        377 
YKRISRVEFT FPDFVTEGAR DLISRLLKHN PSQRPMLREV 
       387 
LEHPWITANS SK
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X287,X288