6GQL

KIT (Mast/stem cell growth factor receptor Kit)
Group: TYR
Uniprot: KIT_HUMAN
Organism: Homo sapiens
Domain boundary: 589 - 926
Resolu: 2.01

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout BBAminus in-in out-in F8B Type2 568 - 931 0
B Inactive DFGout BBAminus in-in out-out F8B Type2 577 - 931 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       556        566        576        586 
gshmpmyevq wkvveesngn nysyidptql PYDHKWEFPR 
       596        606        616        626 
NRLSFGKTLG AGAFGKVVEA TAQGLIKSDA AMTVAVKMLK 
       636        646        656        666 
PSAHSTEREA LMSELKVLSY LGNHENIVNL LGACTHGGPT 
       676        686        757        766 
LVITEYCCYG DLLNFLRRKR DEFVPYKvap edlykdFLTL 
       776        786        796        806 
EHLLSFSYQV AKGMAFLASK NCIHRDLAAR NILLTHGNIT 
       816        826        836        846 
KICDFGLARD IKNDSNYVDK GNARLPVKWM APESIFNSVY 
       856        866        876        886 
TFESDVWSYG IFLWELFSLG SSPYPGMPVD SKFYKMIKEG 
       896        906        916        926 
FRMSSPEYAP AEMYDIMKTC WDADPDKRPT FKQIVQDIEK 

QISEStnh
Lower-case residues are disordered in structure.
Mutations: I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D
Phosphorylation: None