6ED6

ROCK2 (Rho-associated protein kinase 2)
Group: AGC
Uniprot: ROCK2_HUMAN
Organism: Homo sapiens
Domain boundary: 92 - 354
Resolu: 2.86

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in J0P Type1 27 - 415 0
B Inactive DFGin BLAminus in-in in-out J0P Type1.5_Front 28 - 416 12
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         -          -         32         42 
msyyhhhhhh dydipttenl yfqgqRKLEA LIRDPRSPIN 
        52         62         72         82 
VESLLDGLNS LVLDLDFPAL RKNKNIDNFL NRYEKIVKKI 
        92        102        112        122 
RGLQMKAEDY DVVKVIGRGA FGEVQLVRHK ASQKVYAMKL 
       132        142        152        162 
LSKFEMIKRS DSAFFWEERD IMAFANSPWV VQLFYAFQDD 
       172        182        192        202 
RYLYMVMEYM PGGDLVNLMS NYDVPEKWAK FYTAEVVLAL 
       212        222        232        242 
DAIHSMGLIH RDVKPDNMLL DKHGHLKLAD FGTCMKMdet 
       252        262        272        282 
gmvhcdtavG TPDYISPEVL KSqggdgfYG RECDWWSVGV 
       292        302        312        322 
FLYEMLVGDT PFYADSLVGT YSKIMDHKNS LCFPEDAEIS 
       332        342        352        362 
KHAKNLICAF LTDREVRLGR NGVEEIRQHP FFKNDQWHWD 
       372        382        392        402 
NIRETAAPVV PELSSDIDSS NFDDIeddkg dvETFPIPKA 
       412 
FVGNQLPFIG FTYYr
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None