5UP3

MAP3K5 (Mitogen-activated protein kinase kinase kinase 5)
Group: STE
Uniprot: M3K5_HUMAN
Organism: Homo sapiens
Domain boundary: 673 - 938
Resolu: 2.95

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in 8GS Type1 670 - 940 8
B Active DFGin BLAminus in-in in-in 8GS Type1 671 - 939 11
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       679        689        699        709 
lLEYDYEYDE NGDRVVLGKG TYGIVYAGRD LSNQVRIAIK 
       719        729        739        749 
EIPERdsrys qPLHEEIALH KHLKHKNIVQ YLGSFSENGF 
       759        769        779        789 
IKIFMEQVPG GSLSALLRSK WGPLKDNEQT IGFYTKQILE 
       799        809        819        829 
GLKYLHDNQI VHRDIKGDNV LINTYSGVLK ISDFGTSKRL 
       839        849        859        869 
aginpctetf tGTLQYMAPE IIDkgprGYG KAADIWSLGC 
       879        889        899        909 
TIIEMATGKP PFYelgepQA AMFKVGMFKV HPEIPESMSA 
       919        929        939 
EAKAFILKCF EPDPDKRACA NDLLVDEFLK v
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None