5TOE

PIM1 (Serine/threonine-protein kinase pim-1)
Group: CAMK
Uniprot: PIM1_HUMAN
Organism: Homo sapiens
Domain boundary: 38 - 290
Resolu: 2.301

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in 7GK Type1 34 - 306 0
Representative sequence - Chain A
43 53 63 73
LESQYQVGPL LGSGGFGSVY SGIRVSDNLP VAIKHVEKDR
83 93 103 113
ISDWGELPNg TRVPMEVVLL KKVSSGFSGV IRLLDWFERP
123 133 143 153
DSFVLILERP EPVQDLFDFI TERGALQEEL ARSFFWQVLE
163 173 183 193
AVRHCHNCGV LHRDIKDENI LIDLNRGELK LIDFGSGALL
203 213 223 233
KDTVYTDFDG TRVYSPPEWI RYHRYHGRSA AVWSLGILLY
243 253 263 273
DMVCGDIPFE HDEEIIRGQV FFRQRVSSEC QHLIRWCLAL
283 293 303
RPSDRPTFEE IQNHPWMQDV LLPQETAEIH LHS
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None