5MRD

PDPK1 (3-phosphoinositide-dependent protein kinase 1)
Group: AGC
Uniprot: PDPK1_HUMAN
Organism: Homo sapiens
Domain boundary: 82 - 342
Resolu: 1.41

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in ATP Type1 76 - 359 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
        59         69         79         89 
amdgtaaepr pgagslqhaq pppqprSKRP EDFKFGKILG 
        99        109        119        129 
EGSFSTVVLA RELATSREYA IKIVEKRHVN KENKIPYVQR 
       139        149        159        169 
EKDVMSRLDH PFFVKLYFCF QDDEKLYFGL SYAKNGELLK 
       179        189        199        209 
YIRKIGSFDE TCTRFYTAEI VSALEYLHGK GIIHRDLKPE 
       219        229        239        249 
NILLNEDMHI QITDFGTAKV LSPESKQARA NSFVGTAQYV 
       259        269        279        289 
SPELLTEKSA CKSSDLWALG CIIYQLVAGL PPFRAGNEGL 
       299        309        319        329 
IFAKIIKLEY DFPEKFFPKA RDLVEKLLVL DATKRLGCEE 
       339        349        359 
MEGYGPLKAH PFFESVTWEN LHQQTPPKLT
Lower-case residues are disordered in structure.
Mutations: K76S,L113V,I118V,I119N,V124I,T128Q,R131K,T148C
Phosphorylation: X241