5LVP

PDPK1 (3-phosphoinositide-dependent protein kinase 1)
Group: AGC
Uniprot: PDPK1_HUMAN
Organism: Homo sapiens
Domain boundary: 82 - 342
Resolu: 2.5

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in ATP Type1 75 - 359 9
B Active DFGin BLAminus in-in in-in ATP Type1 74 - 359 9
C Active DFGin BLAminus in-in in-in ATP Type1 75 - 359 9
D Active DFGin BLAminus in-in in-in ATP Type1 74 - 359 9
Representative sequence - Chain D
58 68 78 88
gamdgtaaep rpgagslqha qpppqPRKKR PEDFKFGKIL
98 108 118 128
GEGSFSTVVL ARELATSREY AIKILEKRHI IKENKVPYVT
138 148 158 168
RERDVMSRLD HPFFVKLYFT FQDDEKLYFG LSYAKNGELL
178 188 198 208
KYIRKIGSFD ETCTRFYTAE IVSALEYLHG KGIIHRDLKP
218 228 238 248
ENILLNEDMH IQITDFGTAK VLspeskqar aNSFVGTAQY
258 268 278 288
VSPELLTEKS ACKSSDLWAL GCIIYQLVAG LPPFRAGNEG
298 308 318 328
LIFAKIIKLE YDFPEKFFPK ARDLVEKLLV LDATKRLGCE
338 348 358
EMEGYGPLKA HPFFESVTWE NLHQQTPPKL T
Lower-case residues are disordered in structure.
Mutations: Y288G,Q292A
Phosphorylation: X241