5FTO

ALK (ALK tyrosine kinase receptor)
Group: TYR
Uniprot: ALK_HUMAN
Organism: Homo sapiens
Domain boundary: 1116 - 1385
Resolu: 2.22

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in out-in YMX Type1 1094 - 1401 7
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
      1102       1112       1122       1132 
GPNYCFAGKT SSISDLKEVP RKNITLIRGL GHGAFGEVYE 
      1142       1152       1162       1172 
GQVSGMpndp SPLQVAVKTL PEVCSEQDEL DFLMEALIIS 
      1182       1192       1202       1212 
KFNHQNIVRC IGVSLQSLPR FILLELMAGG DLKSFLRETR 
      1222       1232       1242       1252 
PRPSQPSSLA MLDLLHVARD IACGCQYLEE NHFIHRDIAA 
      1262       1272       1282       1292 
RNCLLTCPGP GRVAKIGDFG MARDIYRasy yrkgGCAMLP 
      1302       1312       1322       1332 
VKWMPPEAFM EGIFTSKTDT WSFGVLLWEI FSLGYMPYPS 
      1342       1352       1362       1372 
KSNQEVLEFV TSGGRMDPPK NCPGPVYRIM TQCWQHQPED 
      1382       1392       1402 
RPNFAIILER IEYCTQDPDV INTALPIEYg plvee
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None