4Z55

ALK (ALK tyrosine kinase receptor)
Group: TYR
Uniprot: ALK_HUMAN
Organism: Homo sapiens
Domain boundary: 1116 - 1385
Resolu: 1.55

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in out-out 4LO Type1 1093 - 1399 1
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
      1081       1091       1101       1111 
elqspeykls klrtstimtd yNPNYCFAGK TSSISDLKEV 
      1121       1131       1141       1151 
PRKNITLIRG LGHGAFGEVY EGQVSgmpnd psPLQVAVKT 
      1161       1171       1181       1191 
LPEVCSEQDE LDFLMEALII SKFNHQNIVR CIGVSLQSLP 
      1201       1211       1221       1231 
RFILLELMAG GDLKSFLRET RPRPsqpssL AMLDLLHVAR 
      1241       1251       1261       1271 
DIACGCQYLE ENHFIHRDIA ARNCLLTCPG PGRVAKIGDF 
      1281       1291       1301       1311 
GMARDIYRAG YYrKGGCAML PVKWMPPEAF MEGIFTSKTD 
      1321       1331       1341       1351 
TWSFGVLLWE IFSLGYMPYP SKSNQEVLEF VTSGGRMDPP 
      1361       1371       1381       1391 
KNCPGPVYRI MTQCWQHQPE DRPNFAIILE RIEYCTQDPD 
      1401 
VINTALPIey gplveeeek
Lower-case residues are disordered in structure.
Mutations: S1281G
Phosphorylation: None