4MKC

ALK (ALK tyrosine kinase receptor)
Group: TYR
Uniprot: ALK_HUMAN
Organism: Homo sapiens
Domain boundary: 1116 - 1385
Resolu: 2.01

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in out-out 4MK Type1 1093 - 1401 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         -          -       1073       1083 
msyyhhhhhh dydipttenl yfqgamgsel qspeyklskl 
      1093       1103       1113       1123 
rtstimtdyN PNYCFAGKTS SISDLKEVPR KNITLIRGLG 
      1133       1143       1153       1163 
HGAFGEVYEG QVSgmpndpS PLQVAVKTLP EVCSEQDELD 
      1173       1183       1193       1203 
FLMEALIISK FNHQNIVRCI GVSLQSLPRF ILLELMAGGD 
      1213       1223       1233       1243 
LKSFLRETRP RPSQPSSLAM LDLLHVARDI ACGCQYLEEN 
      1253       1263       1273       1283 
HFIHRDIAAR NCLLTCPGPG RVAKIGDFGM ARDIYRAGYY 
      1293       1303       1313       1323 
RKGGCAMLPV KWMPPEAFME GIFTSKTDTW SFGVLLWEIF 
      1333       1343       1353       1363 
SLGYMPYPSK SNQEVLEFVT SGGRMDPPKN CPGPVYRIMT 
      1373       1383       1393       1403 
QCWQHQPEDR PNFAIILERI EYCTQDPDVI NTALPIEYgp 

lveeeek
Lower-case residues are disordered in structure.
Mutations: S1281G
Phosphorylation: None