4KAO

PTK2 (Focal adhesion kinase 1)
Group: TYR
Uniprot: FAK1_HUMAN
Organism: Homo sapiens
Domain boundary: 422 - 678
Resolu: 2.39

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout BBAminus in-in none-out KAO Type2 415 - 686 17
B Inactive DFGout BBAminus in-out none-out KAO Type2 414 - 686 17
Representative sequence - Chain B
417 427 437 447
gsgstrDYEI QRERIELGRC IGEGQFGDVH QGIYMSPenP
457 467 477 487
ALAVAIKTCK NCTSDSVREK FLQEALTMRQ FDHPHIVKLI
497 507 517 527
GVITENPVWI IMELCTLGEL RSFLQVRKYS LDLASLILYA
537 547 557 567
YQLSTALAYL ESKRFVHRDI AARNVLVSSN DCVKLGDFGl
577 587 597 607
srymedstyy kaskgkLPIK WMAPESINFR RFTSASDVWM
617 627 637 647
FGVCMWEILM HGVKPFQGVK NNDVIGRIEN GERLPMPPNC
657 667 677 687
PPTLYSLMTK CWAYDPSRRP RFTELKAQLS TILEEEKAQq

ee
Lower-case residues are disordered in structure.
Mutations: P410G
Phosphorylation: None