4HOK

CSNK1E (Casein kinase I isoform epsilon)
Group: CK1
Uniprot: KC1E_HUMAN
Organism: Homo sapiens
Domain boundary: 9 - 275
Resolu: 2.77

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 1 - 294 0
C Active DFGin BLAminus in-in in-in No_ligand No_ligand 2 - 294 0
E Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 1 - 294 0
G Active DFGin BLAminus in-in in-in No_ligand No_ligand 1 - 294 0
I Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 1 - 294 0
K Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 1 - 294 0
M Active DFGin BLAminus in-in in-in No_ligand No_ligand 4 - 294 0
O Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 1 - 294 0
Q Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 1 - 294 0
S Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 4 - 294 0
U Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 1 - 293 0
W Active DFGin BLAminus in-in in-in No_ligand No_ligand 2 - 294 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain W
         8         18         28         38 
gsmELRVGNK YRLGRKIGSg sfgDIYLGAN IASGEEVAIK 
        48         58         68         78 
LECVKTKHPQ LHIESKFYKM MQGGVGIPSI KWCGAEGDYN 
        88         98        108        118 
VMVMELLGPS LEDLFNFCSR KFSLKTVLLL ADQMISRIEY 
       128        138        148        158 
IHSKNFIHRD VKPDNFLMGL GKKGNLVYII DFGLAKKYRD 
       168        178        188        198 
ARTHQHIPYR ENKNLTGTAR YASINTHLGI EQSRRDDLES 
       208        218        228        238 
LGYVLMYFNL GSLPWQGLKA ATKRQKYERI SEKKMSTPIE 
       248        258        268        278 
VLCKGYPSEF STYLNFCRSL RFDDKPDYSY LRQLFRNLFH 
       288 
RQGFSYDYVF DWNMLK
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None