4FOD

ALK (ALK tyrosine kinase receptor)
Group: TYR
Uniprot: ALK_HUMAN
Organism: Homo sapiens
Domain boundary: 1116 - 1385
Resolu: 2.0

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in out-in 0UV Type1 1085 - 1405 7
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
      1087       1097       1107       1117 
yklsklrTST IMTDYNPNYS FAGKTSSISD LKEVPRKNIT 
      1127       1137       1147       1157 
LIRGLGHGAF GEVYEGQVSg mpndpSPLQV AVKTLPEVCS 
      1167       1177       1187       1197 
EQDELDFLME ALIISKFNHQ NIVRCIGVSL QSLPRFILLE 
      1207       1217       1227       1237 
LMAGGDLKSF LRETRPRPSQ PSSLAMLDLL HVARDIACGC 
      1247       1257       1267       1277 
QYLEENHFIH RDIAARNCLL TCPGPGRVAK IGDFGMARDI 
      1287       1297       1307       1317 
YRAsyyrkgg CAMLPVKWMP PEAFMEGIFT SKTDTWSFGV 
      1327       1337       1347       1357 
LLWEIFSLGY MPYPSKSNQE VLEFVTSGGR MDPPKNCPGP 
      1367       1377       1387       1397 
VYRIMTQCWQ HQPEDRPNFA IILERIEYCT QDPDVINTAL 
      1407 
PIEYGPLVee eek
Lower-case residues are disordered in structure.
Mutations: C1097S
Phosphorylation: None