4BIB

MAP3K5 (Mitogen-activated protein kinase kinase kinase 5)
Group: STE
Uniprot: M3K5_HUMAN
Organism: Homo sapiens
Domain boundary: 673 - 938
Resolu: 2.43

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus out-out in-in IEO Type1 670 - 939 8
B Inactive DFGin BLAminus in-out in-in IEO Type1 670 - 940 9
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       669        679        689        699 
steegdcesd LLEYDYEYDE NGDRVVLGKG TYGIVYAGRD 
       709        719        729        739 
LSNQVRIAIK EIPERdsryS QPLHEEIALH KHLKHKNIVQ 
       749        759        769        779 
YLGSFSENGF IKIFMEQVPG GSLSALLRSK WGPLKDNEQT 
       789        799        809        819 
IGFYTKQILE GLKYLHDNQI VHRDIKGDNV LINTYSGVLK 
       829        839        849        859 
ISDFGTSKRL aginpcteeF TGTLQYMAPE IIDKGPRGYG 
       869        879        889        899 
KAADIWSLGC TIIEMATGKP PFYELGEPQA AMFKVGMFKV 
       909        919        929        939 
HPEIPESMSA EAKAFILKCF EPDPDKRACA NDLLVDEFLK 
       949        959        969 
Vsskkkktqp klsalsagsn eylrsislpv pvlvedts
Lower-case residues are disordered in structure.
Mutations: T838E
Phosphorylation: None