4BF2

MAP3K5 (Mitogen-activated protein kinase kinase kinase 5)
Group: STE
Uniprot: M3K5_HUMAN
Organism: Homo sapiens
Domain boundary: 673 - 938
Resolu: 2.11

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A None DFGin BLAminus out-none in-in STU Type1 671 - 939 6
B None DFGin BLAminus in-none in-in STU Type1 671 - 940 9
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         -        663        673        683 
mdykddddke nlyfqgstee gdcesdlLEY DYEYDENGDR 
       693        703        713        723 
VVLGKGTYGI VYAGRDLSNQ VRIAIKEIPE Rdsrysqplh 
       733        743        753        763 
EEIALHKHLK HKNIVQYLGS FSENGFIKIF MEQVPGGSLS 
       773        783        793        803 
ALLRSKWGPL KDNEQTIGFY TKQILEGLKY LHDNQIVHRD 
       813        823        833        843 
IKGDNVLINT YSGVLKISDF GTSKRLAgin pcteefTGTL 
       853        863        873        883 
QYMAPEIIDK GPRGYGKAAD IWSLGCTIIE MATGKPPFYE 
       893        903        913        923 
LGEPQAAMFK VGMFKVHPEI PESMSAEAKA FILKCFEPDP 
       933        943        953        963 
DKRACANDLL VDEFLKVssk kkktqpklsa lsagsneylr 
       973 
sislpvpvlv edts
Lower-case residues are disordered in structure.
Mutations: T838E
Phosphorylation: None