3W2C

AURKA (Aurora kinase A)
Group: CAMK
Uniprot: AURKA_HUMAN
Organism: Homo sapiens
Domain boundary: 133 - 383
Resolu: 2.45

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive None None out-out none-none N15 Type1.5_Back 128 - 388 17
C Inactive None None out-out none-none N15 Type1 128 - 388 17
E Inactive None None out-out none-none N15 Type1 128 - 388 17
G Inactive None None out-out none-none N15 Type1.5_Back 128 - 388 17
Representative sequence - Chain G
137 147 157 167
WALEDFEIGR PLGKGKFGNV YLAREKQSKF ILALKVLFKA
177 187 197 207
Qlekagvehq lrrEVEIQSH LRHPNILRLY GYFHDATRVY
217 227 237 247
LILEYAPLGT VYRELQKLSK FDEQRTATYI TELANALSYC
257 267 277 287
hskrvihrdi KPENLLLGSA GELKIADfgw svhapssrrt
297 307 317 327
tlcgTLDYLP PEMIEgrmhd ekVDLWSLGV LCYEFLVGKP
337 347 357 367
PFEANTYQet YKRISRVEFT FPDFVTEGAR DLISRLLKHN
377 387
Psqrpmlrev leHPWITANS S
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None