3TT0

FGFR1 (Fibroblast growth factor receptor 1)
Group: TYR
Uniprot: FGFR1_HUMAN
Organism: Homo sapiens
Domain boundary: 478 - 756
Resolu: 2.8

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAplus in-in out-out 07J Type1.5_Back 461 - 765 0
B Inactive DFGin BLAplus in-in none-none 07J Type1.5_Back 459 - 763 17
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         -          -          -          - 
mgyyhhhhhh dydipttenl yfngmgyyhh hhhhdydipt 
       457        467        477        487 
tenlyfqgml aGVSEYELPE DPRWELPRDR LVLGKPLGEG 
       497        507        517        527 
AFGQVVLAEA IGLDKDKPNR VTKVAVKMLK SDATEKDLSD 
       537        547        557        567 
LISEMEMMKM IGKHKNIINL LGACTQDGPL YVIVEYASKG 
       577        587        597        607 
NLREYLQARR ppgleysynp shnpeeQLSS KDLVSCAYQV 
       617        627        637        647 
ARGMEYLASK KCIHRDLAAR NVLVTEDNVM KIADFGLArd 
       657        667        677        687 
ihhidyykkt tngrlPVKWM APEALFDRIY THQSDVWSFG 
       697        707        717        727 
VLLWEIFTLG GSPYPGVPVE ELFKLLKEGH RMDKPSNCTN 
       737        747        757          - 
ELYMMMRDCW HAVPSQRPTF KQLVEDLDRI VALTSNqemg 
         -          - 
yyhhhhhhdy dipttenlyf ng
Lower-case residues are disordered in structure.
Mutations: C584S
Phosphorylation: None