3E5A

AURKA (Aurora kinase A)
Group: CAMK
Uniprot: AURKA_HUMAN
Organism: Homo sapiens
Domain boundary: 133 - 383
Resolu: 2.3

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus out-out in-in VX6 Type1 125 - 389 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       133        143        153        163 
gKRQWALEDF EIGRPLGKGK FGNVYLAREK QSKFILALKV 
       173        183        193        203 
LFKAQLEKAG VEHQLRREVE IQSHLRHPNI LRLYGYFHDA 
       213        223        233        243 
TRVYLILEYA PLGTVYRELQ KLSKFDEQRT ATYITELANA 
       253        263        273        283 
LSYCHSKRVI HRDIKPENLL LGSAGELKIA DFGWSVHAPS 
       293        303        313        323 
SRRTTLCGTL DYLPPEMIEG RMHDEKVDLW SLGVLCYEFL 
       333        343        353        363 
VGKPPFEANT YQETYKRISR VEFTFPDFVT EGARDLISRL 
       373        383 
LKHNPSQRPM LREVLEHPWI TANSSKps
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X288