3DJ7

AURKA (Aurora kinase A)
Group: CAMK
Uniprot: AURKA_MOUSE
Organism: Mus musculus
Domain boundary: 124 - 374
Resolu: 2.8

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus out-out in-out AK7 Type1.5_Front 117 - 379 6
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       120        130        140        150 
gplgskRQWT LEDFDIGRPL GKGKFGNVYL ARERQSKFIL 
       160        170        180        190 
ALKVLFKTQL EKAGVEHQLR REVEIQSHLR HPNILRLYGY 
       200        210        220        230 
FHDATRVYLI LEYAPLGTVY RELQKLSRFD EQRTATYITE 
       240        250        260        270 
LANALSYCHS KRVIHRDIKP ENLLLGSNGE LKIADFGWSV 
       280        290        300        310 
HAPSsrrttl CGTLDYLPPE MIEGRMHDEK VDLWSLGVLC 
       320        330        340        350 
YEFLVGMPPF EAHTYQETYR RISRVEFTFP DFVTEGARDL 
       360        370        380 
ISRLLKHNAS QRLTLAEVLE HPWIKANSSk ps
Lower-case residues are disordered in structure.
Mutations: N164G,K218R,M280L
Phosphorylation: None