3CPB

KDR (Vascular endothelial growth factor receptor 2)
Group: TYR
Uniprot: VGFR2_HUMAN
Organism: Homo sapiens
Domain boundary: 834 - 1162
Resolu: 2.7

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout None in-in none-out C92 Type2 819 - 1171 19
B Inactive DFGout BBAminus in-in none-out C92 Type1 820 - 1165 18
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       824        834        844        854 
ehaerLPYDA SKWEFPRDRL KLGKPLgrga fGQVIEADAF 
       864        874        884        894 
GIDKTATCRT VAVKMLkegA THSEHRALMS ELKILIHIGH 
       904        914        924        934 
HLNVVNLLGA CTKPGGPLMV ITEFCKFGNL STYLRSKRNE 
       994       1004       1014       1024 
FVPYKvaped lyKDFLTLEH LICYSFQVAK GMEFLASRKC 
      1034       1044       1054       1064 
IHRDLAARNI LLSEKNVVKI CDFGlardiy kdpdyvrkgd 
      1074       1084       1094       1104 
arLPLKWMAP ETIFDRVYTI QSDVWSFGVL LWEIFSLGAS 
      1114       1124       1134       1144 
PYPGVKIDEE FCRRLKEGTR MRAPDYTTPE MYQTMLDCWH 
      1154       1164          - 
GEPSQRPTFS ELVEHLGNLL Qanaqqdrhh hhhh
Lower-case residues are disordered in structure.
Mutations: C817A,V916T,E990V
Phosphorylation: X1054,X1059