3COH

AURKA (Aurora kinase A)
Group: CAMK
Uniprot: AURKA_HUMAN
Organism: Homo sapiens
Domain boundary: 133 - 383
Resolu: 2.7

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive None None out-out none-out 83H Type1 128 - 388 14
B Inactive None None out-out none-out 83H Type1 128 - 388 14
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       133        143        153        163 
akrqWALEDF EIGRPLGKGK FGNVYLAREK NSKFILALKV 
       173        183        193        203 
LFKAQLEKAG VEHQLRREVE IQSHLRHPNI LRLYGYFHDS 
       213        223        233        243 
TRVYLILEYA PLGTVYRELQ KLSKFDEQRT ATYITELANA 
       253        263        273        283 
LSYCHSKKVI HRDIKPENLL LGSAGELKIA Dfgwsvhaps 
       293        303        313        323 
srraaLCGTL DYLPPEMIEG RMHDEKVDLW SLGVLCYEFL 
       333        343        353        363 
VGKPPFEANT YQDTYKRISR VEFTFPDFVT EGARDLISRL 
       373        383 
LKHNPSQRPM LREVLEHPWI TANSSkps
Lower-case residues are disordered in structure.
Mutations: K124A,Q154N,A203S,R251K,T287A,T288A,E336D
Phosphorylation: None