| Chain id | Activity_label | Spatial_label | Dihedral_label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|
| A | Inactive | DFGin | None | none-none | out-out | ANP | Type1 | 13 - 292 | 15 |
| B | Inactive | DFGin | BLBtrans | out-out | out-none | ANP | Type1 | 9 - 292 | 12 |
| C | Inactive | DFGin | BLBtrans | out-out | out-out | ANP | Type1 | 9 - 292 | 5 |
| D | Inactive | DFGin | BLBtrans | out-out | out-out | ANP | Type1 | 6 - 298 | 9 |
Representative sequence - Chain D
10 20 30 40
msedsSALPW SINRDDYELQ EVIGSGATAV VQAAYCAPKK
50 60 70 80
EKVAIKRINL EKCQTSMDEL LKEIQAMSQC HHPNIVSYYT
90 100 110 120
SFVVKDELWL VMKLLSGGSV LDIIKHIVAK GEHKSGVLDE
130 140 150 160
STIATILREV LEGLEYLHKN GQIHRDVKAG NILLGEDGSV
170 180 190 200
QIADFGVSAF LATGGditrn kvrkTFVGTP CWMAPEVMEQ
210 220 230 240
VRGYDFKADI WSFGITAIEL ATGAAPYHKY PPMKVLMLTL
250 260 270 280
QNDPPSLETG VQDKEMLKKY GKSFRKMISL CLQKDPEKRP
290 300
TAAELLRHKF FQKAKNKEfl qek