2P4I

TEK (Angiopoietin-1 receptor)
Group: TYR
Uniprot: TIE2_HUMAN
Organism: Homo sapiens
Domain boundary: 824 - 1094
Resolu: 2.5

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout BBAminus in-in out-in MR9 Type2 838 - 1117 5
B Inactive DFGout None in-in none-out MR9 Type2 836 - 1117 12
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       817        827        837        847 
knnpdptiyp vldwndikfq dvigegnfGQ VLKARIkkdg 
       857        867        877        887 
lRMDAAIKRM KEyasKDDHR DFAGELEVLC KLGHHPNIIN 
       897        907        917        927 
LLGACEHrgy lYLAIEYAPH GNLLDFLRKS RVLETDPAFA 
       937        947        957        967 
IANSTASTLS SQQLLHFAAD VARGMDYLSQ KQFIHRDLAA 
       977        987        997       1007 
RNILVGENYV AKIADFGLsr gqevyvkktm GRLPVRWMAI 
      1017       1027       1037       1047 
ESLNYSVYTT NSDVWSYGVL LWEIVSLGGT PYCGMTCAEL 
      1057       1067       1077       1087 
YEKLPQGYRL EKPLNCDDEV YDLMRQCWRE KPYERPSFAQ 
      1097       1107       1117 
ILVSLNRMLE ERKTYVNTTL YEKFTYAGID csaeeaa
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None