2C6E

AURKA (Aurora kinase A)
Group: CAMK
Uniprot: AURKA_HUMAN
Organism: Homo sapiens
Domain boundary: 133 - 383
Resolu: 2.1

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout BBAminus out-out none-out HPM Type1.5_Back 127 - 389 12
B Inactive None None out-out none-in HPM Type1.5_Front 127 - 388 16
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       128        138        148        158 
gshmskkrQW ALEDFEIGRP LGKGKFGNVY LAREKQSKFI 
       168        178        188        198 
LALKVLFKAQ LEKAGVEHQL RREVEIQSHL RHPNILRLYG 
       208        218        228        238 
YFHDATRVYL ILEYAPLGTV YRELQKLSKF DEQRTATYIT 
       248        258        268        278 
ELANALSYCH SKRVIHRDIK PENLLLGSAG ELKIADfgws 
       288        298        308        318 
vhapssrrtd lcGTLDYLPP EMIEGRMHDE KVDLWSLGVL 
       328        338        348        358 
CYEFLVGKPP FEANTYQETY KRISRVEFTF PDFVTEGARD 
       368        378        388        398 
LISRLLKHNP SQRPMLREVL EHPWITANSS kpsncqnkes 

ask
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None