NTRK2 (BDNF/NT-3 growth factors receptor)

Group: TYR

Uniprot: NTRK2_HUMAN

Domain boundary: 538 - 809

Total number of chains: 5

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	AF-Q16620-K1A
DFGin	None	1	4AT3A
DFGout	BBAminus	1	4AT4A
DFGout	None	2	4AT5A

Database table as tsv

PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
AF-Q16620-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	530 - 817	None	None	0
4AT3A	1.77	Inactive	DFGin	None	out-out	out-in	LTI	Type1	527 - 822	None	None	2
4AT4A	2.36	Inactive	DFGout	BBAminus	in-out	out-in	T6E	Type2	527 - 822	None	None	0
4ASZA	1.7	Inactive	DFGout	None	in-out	out-in	No_ligand	No_ligand	527 - 822	None	None	0
4AT5A	1.71	Inactive	DFGout	None	in-out	out-in	MUJ	Type2	527 - 822	None	None	0

NTRK2 (BDNF/NT-3 growth factors receptor)

Group: TYR

Total number of chains: 5

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	AF-Q16620-K1A
DFGin	None	1	4AT3A
DFGout	BBAminus	1	4AT4A
DFGout	None	2	4AT5A

Database table as tsv

Organism	UniprotID	PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
Homo sapiens	NTRK2_HUMAN	AF-Q16620-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	530 - 817	None	None	0
Homo sapiens	NTRK2_HUMAN	4AT3A	1.77	Inactive	DFGin	None	out-out	out-in	LTI	Type1	527 - 822	None	None	2
Homo sapiens	NTRK2_HUMAN	4AT4A	2.36	Inactive	DFGout	BBAminus	in-out	out-in	T6E	Type2	527 - 822	None	None	0
Homo sapiens	NTRK2_HUMAN	4ASZA	1.7	Inactive	DFGout	None	in-out	out-in	No_ligand	No_ligand	527 - 822	None	None	0
Homo sapiens	NTRK2_HUMAN	4AT5A	1.71	Inactive	DFGout	None	in-out	out-in	MUJ	Type2	527 - 822	None	None	0

NTRK2 (BDNF/NT-3 growth factors receptor)

No non-human structures known.