| Spatial | Dihedral | Chains | Representative |
|---|---|---|---|
| DFGin | BLAminus | 1 | AF-Q96L34-K1A |
| DFGin | BLBtrans | 1 | 8XFLA |
| DFGin | None | 1 | 5ES1A |
| None | None | 1 | 8XFLB |
| PDB | Resolution | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Mutation | Phosphorylation | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AF-Q96L34-K1A | -1.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 51 - 318 | None | None | 0 |
| 8XFLA | 3.0 | Inactive | DFGin | BLBtrans | out-out | out-none | No_ligand | No_ligand | 54 - 370 | None | None | 11 |
| 5ES1A | 2.8 | Inactive | DFGin | None | in-in | in-none | 5RC | Type1 | 54 - 370 | None | None | 13 |
| 8XFLB | 3.0 | Inactive | None | None | out-out | none-none | No_ligand | No_ligand | 54 - 370 | None | None | 18 |
| Spatial | Dihedral | Chains | Representative |
|---|---|---|---|
| DFGin | BLAminus | 1 | AF-Q96L34-K1A |
| DFGin | BLBtrans | 1 | 8XFLA |
| DFGin | None | 1 | 5ES1A |
| None | None | 1 | 8XFLB |
| Organism | UniprotID | PDB | Resolution | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Mutation | Phosphorylation | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Homo sapiens | MARK4_HUMAN | AF-Q96L34-K1A | -1.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 51 - 318 | None | None | 0 |
| Homo sapiens | MARK4_HUMAN | 8XFLA | 3.0 | Inactive | DFGin | BLBtrans | out-out | out-none | No_ligand | No_ligand | 54 - 370 | None | None | 11 |
| Homo sapiens | MARK4_HUMAN | 5ES1A | 2.8 | Inactive | DFGin | None | in-in | in-none | 5RC | Type1 | 54 - 370 | None | None | 13 |
| Homo sapiens | MARK4_HUMAN | 8XFLB | 3.0 | Inactive | None | None | out-out | none-none | No_ligand | No_ligand | 54 - 370 | None | None | 18 |