MAP2K4 (Dual specificity mitogen-activated protein kinase kinase 4)

Group: STE

Uniprot: MP2K4_HUMAN

Domain boundary: 102 - 367

Total number of chains: 7

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	AF-P45985-K1A
DFGin	BLBplus	3	3ALOA
None	None	3	3VUTB

Database table as tsv

PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
AF-P45985-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	94 - 375	None	None	0
3ALNA	2.3	Inactive	DFGin	BLBplus	out-none	out-none	ANP	Type1	83 - 389	None	None	20
3ALNB	2.3	Inactive	DFGin	BLBplus	out-out	out-none	ANP	Type1	84 - 390	None	None	19
3ALOA	2.6	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1	95 - 389	None	None	0
3VUTA	3.5	Inactive	None	None	none-none	out-none	No_ligand	No_ligand	142 - 388	None	None	21
3VUTB	3.5	Inactive	None	None	out-out	out-out	No_ligand	No_ligand	80 - 373	None	None	8
3ALNC	2.3	Inactive	None	None	none-none	none-none	ANP	Type1	100 - 390	None	None	25

MAP2K4 (Dual specificity mitogen-activated protein kinase kinase 4)

Group: STE

Total number of chains: 7

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	AF-P45985-K1A
DFGin	BLBplus	3	3ALOA
None	None	3	3VUTB

Database table as tsv

Organism	UniprotID	PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
Homo sapiens	MP2K4_HUMAN	AF-P45985-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	94 - 375	None	None	0
Homo sapiens	MP2K4_HUMAN	3ALNA	2.3	Inactive	DFGin	BLBplus	out-none	out-none	ANP	Type1	83 - 389	None	None	20
Homo sapiens	MP2K4_HUMAN	3ALNB	2.3	Inactive	DFGin	BLBplus	out-out	out-none	ANP	Type1	84 - 390	None	None	19
Homo sapiens	MP2K4_HUMAN	3ALOA	2.6	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1	95 - 389	None	None	0
Homo sapiens	MP2K4_HUMAN	3VUTA	3.5	Inactive	None	None	none-none	out-none	No_ligand	No_ligand	142 - 388	None	None	21
Homo sapiens	MP2K4_HUMAN	3VUTB	3.5	Inactive	None	None	out-out	out-out	No_ligand	No_ligand	80 - 373	None	None	8
Homo sapiens	MP2K4_HUMAN	3ALNC	2.3	Inactive	None	None	none-none	none-none	ANP	Type1	100 - 390	None	None	25

MAP2K4 (Dual specificity mitogen-activated protein kinase kinase 4)

No non-human structures known.