Spatial | Dihedral | Chains | Representative |
---|---|---|---|
DFGin | BLAminus | 4 | AF-Q15303-K1A |
DFGin | BLBplus | 6 | 2R4BA |
PDB | Resolution | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Mutation | Phosphorylation | Unresolved residues in A-loop |
---|---|---|---|---|---|---|---|---|---|---|---|---|
AF-Q15303-K1A | -1.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 710 - 984 | None | None | 0 |
3BCEA | 2.5 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 703 - 991 | None | None | 2 |
3BCEB | 2.5 | Inactive | DFGin | BLAminus | in-out | in-in | No_ligand | No_ligand | 703 - 993 | None | None | 2 |
3BCEC | 2.5 | Inactive | DFGin | BLAminus | in-out | in-in | No_ligand | No_ligand | 703 - 990 | None | None | 2 |
3BBWA | 4.0 | Inactive | DFGin | BLBplus | out-out | out-none | No_ligand | No_ligand | 708 - 991 | None | None | 14 |
3BBWB | 4.0 | Inactive | DFGin | BLBplus | out-out | out-none | No_ligand | No_ligand | 708 - 998 | None | None | 14 |
2R4BA | 2.4 | Inactive | DFGin | BLBplus | out-out | out-in | GW7 | Type1.5_Back | 694 - 991 | None | None | 0 |
2R4BB | 2.4 | Inactive | DFGin | BLBplus | out-out | out-in | GW7 | Type1.5_Back | 694 - 991 | None | None | 0 |
3BBTB | 2.8 | Inactive | DFGin | BLBplus | out-out | out-none | FMM | Type1.5_Back | 708 - 998 | None | None | 14 |
3BBTD | 2.8 | Inactive | DFGin | BLBplus | out-out | out-none | FMM | Type1.5_Back | 709 - 988 | None | None | 16 |
Spatial | Dihedral | Chains | Representative |
---|---|---|---|
DFGin | BLAminus | 4 | AF-Q15303-K1A |
DFGin | BLBplus | 6 | 2R4BA |
Organism | UniprotID | PDB | Resolution | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Mutation | Phosphorylation | Unresolved residues in A-loop |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Homo sapiens | ERBB4_HUMAN | AF-Q15303-K1A | -1.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 710 - 984 | None | None | 0 |
Homo sapiens | ERBB4_HUMAN | 3BCEA | 2.5 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 703 - 991 | None | None | 2 |
Homo sapiens | ERBB4_HUMAN | 3BCEB | 2.5 | Inactive | DFGin | BLAminus | in-out | in-in | No_ligand | No_ligand | 703 - 993 | None | None | 2 |
Homo sapiens | ERBB4_HUMAN | 3BCEC | 2.5 | Inactive | DFGin | BLAminus | in-out | in-in | No_ligand | No_ligand | 703 - 990 | None | None | 2 |
Homo sapiens | ERBB4_HUMAN | 3BBWA | 4.0 | Inactive | DFGin | BLBplus | out-out | out-none | No_ligand | No_ligand | 708 - 991 | None | None | 14 |
Homo sapiens | ERBB4_HUMAN | 3BBWB | 4.0 | Inactive | DFGin | BLBplus | out-out | out-none | No_ligand | No_ligand | 708 - 998 | None | None | 14 |
Homo sapiens | ERBB4_HUMAN | 2R4BA | 2.4 | Inactive | DFGin | BLBplus | out-out | out-in | GW7 | Type1.5_Back | 694 - 991 | None | None | 0 |
Homo sapiens | ERBB4_HUMAN | 2R4BB | 2.4 | Inactive | DFGin | BLBplus | out-out | out-in | GW7 | Type1.5_Back | 694 - 991 | None | None | 0 |
Homo sapiens | ERBB4_HUMAN | 3BBTB | 2.8 | Inactive | DFGin | BLBplus | out-out | out-none | FMM | Type1.5_Back | 708 - 998 | None | None | 14 |
Homo sapiens | ERBB4_HUMAN | 3BBTD | 2.8 | Inactive | DFGin | BLBplus | out-out | out-none | FMM | Type1.5_Back | 709 - 988 | None | None | 16 |