DDR2 (Discoidin domain-containing receptor 2)

Group: TYR
Uniprot: DDR2_HUMAN
Domain boundary: 563 - 851


Total number of chains: 14
Spatial Dihedral Chains Representative
DFGin BLAminus 1 AF-Q16832-K1A
DFGout BBAminus 13 6FERD
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-Q16832-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 555 - 855 None None 0
6FERD 2.87 Inactive DFGout BBAminus in-in out-in D6Q Type1 553 - 851 None None 0
6FERI 2.87 Inactive DFGout BBAminus in-out out-in D6Q Type1 555 - 851 None None 0
6FERA 2.87 Inactive DFGout BBAminus in-in out-in D6Q Type2 553 - 851 None None 0
6FERB 2.87 Inactive DFGout BBAminus in-out out-in D6Q Type2 553 - 851 None None 0
6FERC 2.87 Inactive DFGout BBAminus in-in out-in D6Q Type2 553 - 851 None None 0
6FERE 2.87 Inactive DFGout BBAminus in-in out-in D6Q Type2 553 - 851 None None 0
6FERF 2.87 Inactive DFGout BBAminus in-in out-in D6Q Type2 553 - 851 None None 0
6FERG 2.87 Inactive DFGout BBAminus in-in out-in D6Q Type2 553 - 851 None None 0
6FERH 2.87 Inactive DFGout BBAminus in-in out-in D6Q Type2 553 - 851 None None 0
6FERJ 2.87 Inactive DFGout BBAminus in-in out-in D6Q Type2 553 - 851 None None 0
6FERK 2.87 Inactive DFGout BBAminus in-out out-in D6Q Type2 555 - 851 None None 0
6FERL 2.87 Inactive DFGout BBAminus in-out out-in D6Q Type2 554 - 851 None None 0
7AYMA 2.12 Inactive DFGout BBAminus in-out out-in 4VD Type2 558 - 849 E882E,R903R None 8

DDR2 (Discoidin domain-containing receptor 2)

Group: TYR
Total number of chains: 14
Spatial Dihedral Chains Representative
DFGin BLAminus 1 AF-Q16832-K1A
DFGout BBAminus 13 6FERD
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens DDR2_HUMAN AF-Q16832-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 555 - 855 None None 0
Homo sapiens DDR2_HUMAN 6FERD 2.87 Inactive DFGout BBAminus in-in out-in D6Q Type1 553 - 851 None None 0
Homo sapiens DDR2_HUMAN 6FERI 2.87 Inactive DFGout BBAminus in-out out-in D6Q Type1 555 - 851 None None 0
Homo sapiens DDR2_HUMAN 6FERA 2.87 Inactive DFGout BBAminus in-in out-in D6Q Type2 553 - 851 None None 0
Homo sapiens DDR2_HUMAN 6FERB 2.87 Inactive DFGout BBAminus in-out out-in D6Q Type2 553 - 851 None None 0
Homo sapiens DDR2_HUMAN 6FERC 2.87 Inactive DFGout BBAminus in-in out-in D6Q Type2 553 - 851 None None 0
Homo sapiens DDR2_HUMAN 6FERE 2.87 Inactive DFGout BBAminus in-in out-in D6Q Type2 553 - 851 None None 0
Homo sapiens DDR2_HUMAN 6FERF 2.87 Inactive DFGout BBAminus in-in out-in D6Q Type2 553 - 851 None None 0
Homo sapiens DDR2_HUMAN 6FERG 2.87 Inactive DFGout BBAminus in-in out-in D6Q Type2 553 - 851 None None 0
Homo sapiens DDR2_HUMAN 6FERH 2.87 Inactive DFGout BBAminus in-in out-in D6Q Type2 553 - 851 None None 0
Homo sapiens DDR2_HUMAN 6FERJ 2.87 Inactive DFGout BBAminus in-in out-in D6Q Type2 553 - 851 None None 0
Homo sapiens DDR2_HUMAN 6FERK 2.87 Inactive DFGout BBAminus in-out out-in D6Q Type2 555 - 851 None None 0
Homo sapiens DDR2_HUMAN 6FERL 2.87 Inactive DFGout BBAminus in-out out-in D6Q Type2 554 - 851 None None 0
Homo sapiens DDR2_HUMAN 7AYMA 2.12 Inactive DFGout BBAminus in-out out-in 4VD Type2 558 - 849 E882E,R903R None 8

DDR2 (Discoidin domain-containing receptor 2)

No non-human structures known.